Six threads we keep pulling on: what grows in the edge, what lives in it, and what the weather does to both.
The three most recent dispatches, whatever they are about.
Sep 20, 2026
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5 min read
My morning cortisol was 0.49, below the bottom of the range. By October it was 3.9. Only one of my three reasons is about looking younger.
6 min read
A new Neuron paper caught tau running mitochondria backwards. The peptides built for that machinery have never been tested against it.
10 min read
Day 1 of 30 Peptides in 30 Days. Thirty years of animal studies, about 30 humans, and the trial that finally started.